Unraveling the Mystery of “Aorta-Induced Tracheal Cartilage Regeneration”
2026-02-06 National Science and Technology Council
The trachea is the vital passage that sustains breathing. However, when extensive tracheal reconstruction is required due to tumor invasion, trauma, or other causes, there has been a long-standing lack of stable and durable substitute materials clinically—making this one of the most formidable challenges in thoracic surgery. With long-term support from the National Science and Technology Council (NSTC), a research team led by Distinguished Professor Jin-Shing Chen and Assistant Professor Wan-Ting Hung of the Department of Surgery, College of Medicine, National Taiwan University, has provided evidence-based mechanistic insights into the cartilage-regeneration phenomenon observed when cryopreserved aortic allograft is used for tracheal reconstruction. The findings were recently published in the internationally renowned journal “Advanced Healthcare Materials”.